审稿意见(看不懂)
The way that the authors arrive at the S/N = 3 determination is elusive. I just don’t see in comparing the response at 0 and 1 nM DNA conc. how the S/N = 3 is at 0.2 pM when it clearly looks as if at 1nM it is darn close to this level. In addition, I would argue that the S/N = 3 should be compared with a PNA electrode exposed to the non-complementary sequence since there is clearly some signal arising from such conditions (e.g. Fig. 4). :L The way that the authors arrive at the S/N = 3 determination is elusive. I just don’t see in comparing the response at 0 and 1 nM DNA conc. how the S/N = 3 is at 0.2 pM when it clearly looks as if at 1nM it is darn close to this level. In addition, I would argue that the S/N = 3 should be compared with a PNA electrode exposed to the non-complementary sequence since there is clearly some signal arising from such conditions (e.g. Fig. 4).作者测定信噪比3:1(是最低检测限吧?)的方法令人难以捉摸。通过比较在0 nM DNA和1 nM DNA两处浓度下所获得的反应(仪器给出的信号)。我不能看出信噪比3:1怎么会处在0.2 nM的浓度,很明显,它看起来就像是处在1 nM的浓度,它接近于这个浓度。另外,信噪比3:1的测定应该与一个暴露于非互补序列的PNA电极进行比较,因为在这个条件下产生的一些信号是清楚的。 呵呵,很专业嘛。 很专业,看不懂啊 :) 太强了,有点偏离我专业~~ 好好学习 哈哈
萍友好样的 不错的,学习一下。
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